1.
Angew Chem Int Ed Engl
; 56(42): 12962-12966, 2017 10 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28816407
RESUMO
Pyrrolidines are important heterocyclic compounds with endless applications in organic synthesis, metal catalysis, and organocatalysis. Their potential as ligands for first-row transition-metal catalysts inspired a new method to access complex poly-heterocyclic pyrrolidines in one step from available materials. This fundamental step forward is based on the discovery of an essential organoaluminum promoter that engages unactivated and electron-rich olefins in intermolecular [3+2] cycloadditions.